Stem Cell Therapy for Knees: Reviews

Stem cell therapy for knees can make many people relief. Knee pain is a very common disease affecting millions of Americans and people around the world. Given the daily load on the legs, a problem with the knees can restrict movement. Knee pain can significantly affect the quality of life and anti-inflammatory drugs can only do so much. Suffice to say, there is considerable interest in finding solutions to combat pain and restore healthy knee function. This is where stem cell therapy for knees comes into play.

Stem cell for knee treatment

The common task of the articular cartilage is to promote a smooth movement of the articular surfaces and protect the bones from friction. This method allows shock absorption up to 20 times body weight. It is important for physical exercise, especially in athletics.

Osteoarthritis is one of the most common chronic degenerative diseases and often affects the knee, causing articular cartilage to deteriorate over time.

Osteoarthritis may also be due to a knee injury, e.g. As a torn ligament, tendon injury or fracture occur.

If damaged, the joint becomes unstable and the articular cartilage becomes worn. From there, the bone can be damaged in addition to the joint lenses, tendons, ligaments and muscles.

Stem cell therapy for knees is minimally invasive. It is a procedure that can reduce inflammation, slow and repair all of these forms of arthritis damage, and delay or prevent knee replacement.

Why is stem cell therapy important for knees?

With the growing power of regenerative medicine, more physicians can now offer affordable, cost-effective and, above all, long-lasting treatments that treat pain in the short and long term. The stem cell therapy for knees brings with it the possibility to make knee pain pain obsolete.

However, despite the promise of regenerative therapy, it is still important to conduct due diligence before making a decision. This requires understanding some facts about knee pain. These facts include what causes it, how stem cell therapy helps, how it works and who is a good candidate.

Stem Cell Knee Injections

Adult stem cells can be obtained with simple methods from bone marrow or fat. It is then concentrated and injected into the knee with image guidance, usually to successful results.

In one study, patients experienced improvement in both knees, even though only one knee was injected. Although the natural wear of the knee persists after five years, the knees injected with stem cells are in better condition than before the injections.

The researchers believe that stem cell therapy for the knee works by:

  • Develop into essential cartilage cells
  • Prevention of inflammation that can aggravate arthritis
  • Release of proteins, called cytokines, that slow cartilage degradation and reduce pain

Ongoing research is seeking to determine which techniques, cell selection and doses of stem cell therapy provide the most effective and consistent results.

Some seem to be stronger than others and the overall results are promising, but more research is needed.

Types of stem cells for degenerative knee cartilage

The injection of progenitor cells, particularly mesenchymal stem cells, has proven to be a better strategy for repairing degenerative cartilage than the implantation of differentiated cells such as articular cartilage. Adult stem cells have a reliable discrimination in cartilage, bone, fat or soft tissue.

They also show the ability to move in areas of inflammation and degeneration and alter the activity of the immune system, which can favorably affect the surrounding cartilage in areas of damage.

Encouragingly, the results of preclinical and clinical studies provide initial evidence of efficacy and safety in the therapeutic use of mesenchymal stem cell therapies for the treatment of knee cartilage damage and osteoarthritis. Cell-based therapy has become a focal point of tissue engineering research focused on the functional replacement of cartilage and meniscal regeneration.

Side Effects

The stem cell treatment of the knee is non-invasive and rarely painful. Side effects are minimal.

The most common postoperative experiences include mild injection site pain, swelling, and some joint stiffness.

What risks exist?

What risks exist? | Stem cell therapy for knees
The good news about this form of stem cell therapy is that the patient uses his own cells. That is, they completely skip the dangers that donor cells accompany. The most important of these is graft versus host disease (in which the donor cells trigger an immune response against the patient’s body). Since the cells all have the same antibodies, neither the body nor the reintroduced cells repel each other.

Due to the relatively low use of outpatient treatment (as opposed to a bone marrow transplant), the likelihood of something going wrong is significantly reduced.

However, there are risks wherever needles are used. It is possible to get an infection both at the site of the blood collection and at the injection site, but these risks are quite low. Other risks include discoloration at the injection site or pain. While some people fear the possible growth of stem cells at the site of injection into a tumor, this is unlikely as doctors use adult stem cells for these procedures, which have low proliferative capacity.

These adult stem cells tend to be much safer than pluripotent stem cell types. Examples of pluripotent stem cells are embryonic stem cells (derived from embryos) and a type of laboratory-produced stem cell known as an induced pluripotent stem cell.